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Welcome to Dhayalan Group (OMC)

My research focus is on “Total Synthesis of Natural Products and Active Drug Molecules” using organo-/metal-catalysts for the application of biomedical treatments and agriculture. In this line of research, small ligand and substrate libraries bearing substituents that could be systematically varied e.g. steric and electronic perturbations were created and studied for the construction of mathematical models. Using these models, it was possible to predict substituents on the optimal catalyst for certain asymmetric reactions, Regio- and chemo selective reactions. 

Recent paper: Dhayalan et al. Chemical Society Review 2024:  Impact factor: 40.4 

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Dr. V. Dhayalan, Ph.D.

        (Ramanujan Faculty)

 

Organometallics & Catalysis Lab (OMCL)

 

 

Research Homepage: https://vasudeva49.wixsite.com/catalysislab

Position availability (current opening):

PhD: 2 (with JRF, GATE qualified Students)

Project Assistant: 1  

 

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Prof. Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless

The Nobel Prize 2022 for the development of "Click Chemistry" and Bioorthogonal Chemistry

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Prof. Benjamin List   &   Prof.  David WC MacMillan
The Nobel Prize 2021 for developing a new way for building
molecules known as “asymmetric organocatalysis.”

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Prof. Richard F. Heck, Prof. Ei-ichi Negishi, Prof. Akira Suzuki
The Nobel Prize in Chemistry 2010 was awarded jointly to Richard F. Heck, Ei-ichi Negishi and Akira Suzuki "for palladium-catalyzed cross couplings in organic synthesis"

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PAST EVENTS

International Conference on Emerging Trends in Synthetic Organic Chemistry-2021 (ICETSOC-2021)

on 6-7, December 2021 by (Virtual Mode)

Organized by Dr. V. Dhayalan, et al. 

Department of Chemistry

National Institute of Technology Puducherry

Karaikal - 609 609, India

For more details, visit https://nitpychemconf2021.wixsite.com/organic-lab

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RECENT POSITION: 

 

GUEST EDITOR

I am happy to share with you all, I was joined as a Guest Editor in the Journal of Catalysis Research, LiDSEN Group. I am currently organizing a special issue about "New Frontiers in Asymmetric Catalysis" those who are interested to publish your Asymmetric Catalysis work in this journal and submit it via the journal home portal......

http://www.lidsen.com/.../cr-special.../Asymmetric-Catalysis

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RECENT ARTICLES

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17. Aksa S Annie, Marappan Pradeep Kumar, Ramesh Adithya, Kaliswaran Vignesh, Vasudevan Dhayalan* Recent Synthetic Strategies for the Functionalization of Indole and Azaindole Scaffolds Asian. J. Org. Chem. 2024 (Accepted, 202400694)

16. Savita Gat, Rana Chatterjee, Jayshree Solanke, Vasudevan Dhayalan,* and Rambabu Dandela* "Mechanochemical synthesis of phosphoryl amides and esters from diphenylphosphoryl azides under mild conditions" Chemistry Select, 2024, 9, e202404882.
 
 
15.  Vasudevan Dhayalan,* Vishal S. Dodke, Marappan Pradeep Kumar, Hatice Seher Korkmaz, Anja Hoffmann-Röder, Pitchamuthu Amaladass, Rambabu Dandela, Ragupathy Dhanusuramane and Paul Knochel* "Recent synthetic strategies for the functionalization of fused bicyclic heteroaromatics using organo-Li, -Mg and -Zn reagents" Chemical Society Review 2024 (DOI:10.1039/d4cs003369a) Impact factor: 40.4
 
 
14. E. V. Venkat Shivaji Ramarao , Savita Gat , Rana Chatterjee , Jayshree Solanke , Vasudevan Dhayalan , Rambabu Dandela, "NaIO4/NH2OH-mediated Efficient Synthesis of Phosphoroamidates from Anilines and Triethyl PhosphiteSustainability & Circularity NOW 2024 (DOI: 10.1055/a-2386-5537)
13. Deepika Sharma,†  Mahantesh G,†  Marappan Pradeep Kumar,†   Rana Chatterjee,  Rambabu Dandela, Vasudevan Dhayalan,* "Efficient Synthesis of Hydrobenzoin through NHC Catalysis: A Sustainable Approach for C-C Bond Formation" Chemistry Select 2024 (DOI: 10.1002/slct.202403882)   (IF:2.1)
12. Vasudevan Dhayalan,* Modern Synthetic Strategy for Adamantyl Organometallic Reagents and Functionalization of Adamantyl Frameworks"  Chemistry Select 2024 (DOI: 10.1002/slct.202403285). (IF:2.1)

 

11. Marappan Pradeep Kumar, Aksa S Annie, Vikash Kumar Bind, Ramesh Adithya, P Amaladass, Vasudevan Dhayalan* “A review on functionalization of benzo-5,6-fused bicyclic heteroaromatic compounds” Chemistry - An Asian Journal, 2024 (Accepted, n/a, e202400455).

 

10. Deepika Sharma, Rana Chatterjee, Vasudevan Dhayalan,* and Rambabu Dandela,* "Metal-free oxidative coupling of aryl acetylene with elemental sulphur and amines: A facile access to α-ketothioamides" Organic & Biomolecular Chemistry, 2024 (Accepted, https://doi.org/10.1039/D4OB00830H) (IF: 3.2)

9. E. V. Venkat Shivaji Ramarao, Jayshree Solanke, Rana Chatterjee, Savita Gat, Vasudevan Dhayalan, Rambabu Dandela "Metal-free efficient synthesis of aryl sulfonamides from N hydroxy sulfonamide and amines" Organic & Biomolecular Chemistry, 2024 (Accepted, https://doi.org/10.1039/D4OB00878B) (IF: 3.2)

8. Pradeep Kumar, M.; Annie, A. S.; Solanke, J. N.; Dandela, R.* Dhayalan, V.; "A Comprehensive Review on Selective Catalytic Methods for Functionalization of Adamantane Scaffolds" Asian. J. Org. Chem. 2024 (Accepted, DOI: 10.1002/ajoc.202400184)  (IF: 4.1)

7. *Dhayalan, V.; Dodke, V. S.; Sharma, D.; Dandela, R. “Recent advances in the preparation of air stable organozinc pivalates and their applications in organic synthesis” Eur. J. Org. Chem. 2024, (DOI: 10.1002/ejoc.202301263) (IF: 3.34)

 

6. Pradeep Kumar, M.; Mahantesh G.; Amaladass, P.; Manikandan, C.; *Dhayalan, V. Recent synthetic strategies for the construction of functionalized carbazoles and their heterocyclic motifs enabled by Lewis acids” RSC Advances, 2023, 13, 32596-32626. (IF: 4.04)

 

4.* Dhayalan, V.; Sharma, D.; Chatterjee, R.; Dandela, R. “Recent advances in enantioselective organocatalytic reactions enabled by NHCs containing triazolium motifs” Eur. J. Org. Chem. 2023 (https://doi.org/10.1002/ejoc.202300285).(IF: 3.34)

4Mahantesh G.; Sharma, D.; Dandela, R. *Dhayalan, V.“Synthetic Strategies of N-Heterocyclic Olefin (NHOs) and Their Recent Application of Organocatalytic Reactions and Beyond” Chem. Eur. J. 2023 2023, 29, e202302106 (IF: 5.20)

 

3. Deepika Sharma.; Chitrarasu Manikandan.; *Dhayalan. V. and Rambabu Dandela* “Mechanistic Evaluation of Benzoin Catalysis Enabled by Triazolium Salt: Application in the Preparation of Benzil and Heterocycles” Chemistry Select 2023 8, e202303139 (IF: 2.10)

 

2. Dhayalan, V. “Recent advances in organocatalytic methods for the synthesis of deuterated aldehydes” Mini-Reviews in Organic Chemistry 2023, 20, 593-611(IF: 2.49)

 

1Gaware, S.; Chatterjee, R.; Dhayalan, V.; Dandela, R. “Metal-free one-pot synthesis of 2-substituted benzimidazoles from N-aryl Imines and TMSN3” Tetrahedron Letters 2023, 115, 154289 (IF: 2.41)

 

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