Welcome to Dhayalan Group (OMC)
Our OMC group research focus is on “Total Synthesis of Natural Products and Active Drug Molecules” using organo-/metal-catalysts for the application of biomedical treatments and agriculture. In this line of research, small ligand and substrate libraries bearing substituents that could be systematically varied e.g. steric and electronic perturbations were created and studied for the construction of mathematical models. Using these models, it was possible to predict substituents on the optimal catalyst for certain asymmetric reactions, Regio- and chemo selective reactions.
Recent paper: Dhayalan et al. Chemical Society Review 2024: Impact factor: 40.4
Dr. V. Dhayalan, MSc, Ph.D.
(Assistant Professor)
Organometallics & Catalysis Lab (OMC Lab)
Position availability (current opening):
PhD: 2 (with JRF, GATE qualified Students)
Project Assistant: 0
Prof. Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless
The Nobel Prize 2022 for the development of "Click Chemistry" and Bioorthogonal Chemistry
Prof. Benjamin List & Prof. David WC MacMillan
The Nobel Prize 2021 for developing a new way for building
molecules known as “asymmetric organocatalysis.”
Prof. Richard F. Heck, Prof. Ei-ichi Negishi, Prof. Akira Suzuki
The Nobel Prize in Chemistry 2010 was awarded jointly to Richard F. Heck, Ei-ichi Negishi and Akira Suzuki "for palladium-catalyzed cross couplings in organic synthesis"
PAST EVENTS
International Conference on Emerging Trends in Synthetic Organic Chemistry-2021 (ICETSOC-2021)
on 6-7, December 2021 by (Virtual Mode)
Organized by Dr. V. Dhayalan, et al.
Department of Chemistry
National Institute of Technology Puducherry
Karaikal - 609 609, India
For more details, visit https://nitpychemconf2021.wixsite.com/organic-lab
RECENT POSITION:
GUEST EDITOR
I am happy to share with you all, I was joined as a Guest Editor in the Journal of Catalysis Research, LiDSEN Group. I am currently organizing a special issue about "New Frontiers in Asymmetric Catalysis" those who are interested to publish your Asymmetric Catalysis work in this journal and submit it via the journal home portal......
http://www.lidsen.com/.../cr-special.../Asymmetric-Catalysis
RECENT ARTICLES
2025
Vasudevan Dhayalan, "Recent Advances in Strain-Release Functionalization of [1.1.1]Propellanes Using Organometallic Reagents." Synlett 2025. doi: 10.1055/a-2669-6239
Jayshree Nandkumar Solanke, Deepika Sharma, Nalinikant Patra, Rambabu Dandela, Vasudevan Dhayalan* Recent Advances in the Synthesis and Applications of Thiocarbonyl Compounds" Eur. J. Org. Chem. 2025 (DOI: 10.1002/ejoc.202500460R1)
Deepika Sharma, Jayshree Nandkumar Solanke, Savita Gat, Vasudevan Dhayalan*, and Rambabu Dandela. An Alternative Method for the Efficient Synthesis of Aminoindane-Based Chiral Triazolium Salts" ChemistrySelect, 2025 (DOI: 10.1002/slct.70759)
Jayshree Nandkumar Solanke, Selvam Vasanth, Marappan Pradeep Kumar, Mamidisetti Vishnuvardhan, Vasudevan Dhayalan,* and Rambabu Dandela" A green one-pot strategy for the direct synthesis of benzil" Asian. J. Org. Chem. 2025 (https://doi.org/10.1002/202400568)
Pitchamuthu Amaladass, Ragupathy Dhanusuraman, Alphonse Lazer, Devakumar John, Kuppusamy Thangaraju, Vasudevan Dhayalan ."A Comprehensive Exploration of Synthetic Methods for Functionalized Benzo[c]thiophene Derivatives and their Material Science Applications". Asian. J. Org. Chem. 2025 (https://doi.org/10.1002/ajoc.202500085)
2024
Aksa S Annie, Marappan Pradeep Kumar, Ramesh Adithya, Kaliswaran Vignesh, Vasudevan Dhayalan* Recent Synthetic Strategies for the Functionalization of Indole and Azaindole Scaffolds Asian. J. Org. Chem. 2024 (https://doi.org/10.1002/ajoc.202400694)
Vasudevan Dhayalan,* Vishal S. Dodke, Marappan Pradeep Kumar, Hatice Seher Korkmaz, Anja Hoffmann-Röder, Pitchamuthu Amaladass, Rambabu Dandela, Ragupathy Dhanusuramane and Paul Knochel* "Recent synthetic strategies for the functionalization of fused bicyclic heteroaromatics using organo-Li, -Mg and -Zn reagents" Chemical Society Review 2024 (DOI:10.1039/d4cs003369a) Impact factor: 40.4
Marappan Pradeep Kumar, Aksa S Annie, Vikash Kumar Bind, Ramesh Adithya, P Amaladass, Vasudevan Dhayalan* “A review on functionalization of benzo-5,6-fused bicyclic heteroaromatic compounds” Chemistry - An Asian Journal, 2024 (Accepted, n/a, e202400455).
Deepika Sharma, Rana Chatterjee, Vasudevan Dhayalan,* and Rambabu Dandela,* "Metal-free oxidative coupling of aryl acetylene with elemental sulphur and amines: A facile access to α-ketothioamides" Organic & Biomolecular Chemistry, 2024 (Accepted, https://doi.org/10.1039/D4OB00830H) (IF: 3.2)
E. V. Venkat Shivaji Ramarao, Jayshree Solanke, Rana Chatterjee, Savita Gat, Vasudevan Dhayalan, Rambabu Dandela "Metal-free efficient synthesis of aryl sulfonamides from N hydroxy sulfonamide and amines" Organic & Biomolecular Chemistry, 2024 (Accepted, https://doi.org/10.1039/D4OB00878B) (IF: 3.2)
Pradeep Kumar, M.; Annie, A. S.; Solanke, J. N.; Dandela, R.* Dhayalan, V.; "A Comprehensive Review on Selective Catalytic Methods for Functionalization of Adamantane Scaffolds" Asian. J. Org. Chem. 2024 (Accepted, DOI: 10.1002/ajoc.202400184) (IF: 4.1)
Dhayalan, V.; Dodke, V. S.; Sharma, D.; Dandela, R. “Recent advances in the preparation of air stable organozinc pivalates and their applications in organic synthesis” Eur. J. Org. Chem. 2024, (DOI: 10.1002/ejoc.202301263) (IF: 3.34)